Daily Archives: 20 April 2024

Research indicates that middle-aged individuals in America experience greater loneliness compared to their European counterparts, proposing that loneliness during midlife is widespread

Contrary to prevalent assertions, the notion that middle-aged Americans are in the throes of a loneliness epidemic may not hold water. Fresh insights suggest that for individuals aged between 45 and 65, loneliness might be a persistent, ever-present condition rather than an escalating crisis.

Loneliness transcends mere emotional discomfort; it harbours the significant potential to deteriorate physical health, drawing parallels to the health hazards of smoking as many as 15 cigarettes daily. Nevertheless, recent studies have illuminated a concerning trend: not only do middle-aged Americans report higher levels of loneliness compared to their contemporaries in Europe and Israel, but an intergenerational escalation of loneliness is observable in both the U.S. and Europe.

This study, spearheaded by scholars at the Department of Psychology at Arizona State University, has garnered attention through its publication in the journal American Psychologist.

“Especially notable are the soaring loneliness levels among middle-aged Americans, particularly those within the baby boomer demographic. Yet, it’s becoming apparent that middle-aged adults in England, Italy, Spain, and Greece are beginning to exhibit loneliness levels that mirror those of their American counterparts,” commented Frank Infurna, an associate professor of psychology at ASU.

Loneliness arises from the disparity between actual and desired connections with others. It has gained significant recognition as a public health concern, prompted by actions such as the U.S. Surgeon General’s Health Advisory, which aims to mitigate loneliness’s impact. However, the underlying causes remain elusive.

The foundation of this study is comprehensive datasets encompassing nationally representative samples of adults aged 45–65 across 14 countries, including the Health and Retirement Study in the U.S., the English Longitudinal Study of Ageing, and the Survey of Health, Ageing and Retirement in Europe, which cover a wide array of nations.

Examining loneliness trends across various geographies and over time, the researchers observed notable generational differences in loneliness levels among the countries studied.

The baby boomer generation across all 14 countries reported the highest levels of loneliness, with American baby boomers significantly outpacing their international peers.

“For this cohort, the pronounced disparity in loneliness levels between Americans and individuals of the same age in other countries is stark and troubling,” Infurna remarked.

The study revealed a distinct pattern for Generation X, where Americans reported heightened loneliness levels, only marginally surpassed by those in England.

The research also focused on the evolution of loneliness, tracing how loneliness levels fluctuated within each generation as they aged from 45 to 65.

For American baby boomers born between 1946–54, a marked increase in loneliness was noted as they neared 65. For those born after 1955, however, loneliness levels plateaued, albeit at distressingly high levels. This increasing trend was mirrored in Generation X.

Conversely, loneliness levels remained stable among baby boomers in several European countries and Israel. Yet, baby boomers and Generation X saw a sharp rise in loneliness in Italy, Spain, and Greece from ages 40 to 65.

Among all nations studied, middle-aged adults across all generations in Denmark, the Netherlands, and Sweden reported the lowest loneliness. Nevertheless, in these countries, baby boomers also reported the highest levels of loneliness.

Infurna views this study as an initial step towards addressing whether loneliness is widespread or deeply ingrained.

“While individuals can combat isolation and loneliness through community engagement, like volunteering, there’s a critical demand for systemic support. Initiatives aimed at assisting adult caregivers and providing financial support can significantly contribute. Such interventions can afford middle-aged adults, who often balance employment and caregiving responsibilities, the opportunity and resources to foster connections.

“This study’s findings further suggest that the lowest reported loneliness levels correspond with countries that boast comprehensive government-supported safety nets,” Infurna concluded.

More information: Infurna, F. J., Dey, N. E. Y., Gonzalez Avilés, T., Grimm, K. J., Lachman, M. E., & Gerstorf, D. Loneliness in midlife: Historical increases and elevated levels in the United States compared with Europe, American Psychologist. DOI: 10.1037/amp0001322

Journal information: American Psychologist Provided by Arizona State University

Impact of keratin microsphere gel on hair growth in mice

The skin acts as a protective barrier that limits the infiltration of particles and safeguards against external hazards. Recent studies have shown that small particles laden with substances that promote hair growth can bypass this barrier to reach the hair follicles. Research conducted by the University of Tsukuba revealed that the topical use of a gel made from water-soluble oxidized keratin (referred to as keratin microsphere gel) on mice significantly boosted cell proliferation and increased the expression of genes linked to hair growth within the papilla cells of hair follicles, thus encouraging hair growth.

Upon applying the keratin microsphere gel, which is water-based, to the shaved areas on the backs of mice, hair began to regrow from the second day after application, and the speed of hair growth increased over time. This outcome was comparable to that observed with minoxidil, a well-known hair growth enhancer. Additionally, genetic analysis of tissue samples from the dorsal skin of the mice showed a significant increase in the expression of genes that play a role in regulating the hair cycle and maintaining skin balance. Furthermore, a skin model was created to assess the effect of keratin microspheres on papilla cells. This model consisted of a co-culture with an epidermal layer derived from human cells on top and primary human papilla cells underneath. The gene expression analysis in this model confirmed the stimulating effects of keratin microspheres on papilla cells, showcasing the gel’s ability to penetrate through the skin.

This research not only unveils the potential of keratin microsphere gel to promote hair growth but also underscores its safety and productivity. Given that keratin is a vital component of both hair and skin, its use as a hair growth stimulant is expected to be both safe and effective, with minimal risk of adverse side effects.

More information: Meriem Bejaoui et al, Keratin Microspheres as Promising Tool for Targeting Follicular Growth, ACS Applied Bio Materials. DOI: 10.1021/acsabm.3c00956

Journal information: ACS Applied Bio Materials Provided by University of Tsukuba