Daily Archives: 14 June 2024

Heat’s Impact on Ageing Populations: Projections, Vulnerabilities, and Policy Implications in the Context of Climate Change

A Nature Communications paper suggests that up to 246 million older adults globally could face dangerous acute heat exposure by 2050, particularly in Asia and Africa. The study’s findings are crucial for informing regional heat risk assessments and public health decision-making. An interactive visualization dashboard illustrates current and projected demographic shifts and heat-related risks across countries worldwide.

The world’s population is rapidly ageing, with the number of people aged over 60 set to double to nearly 2.1 billion by 2050. This demographic shift is especially pronounced in lower- and middle-income countries, where extreme weather events driven by climate change pose significant risks. The vulnerability of older adults to increasingly frequent and intense heatwaves threatens their physical health, particularly as they are more susceptible to heat-related illnesses and exacerbated health conditions, highlighting the urgent need for climate adaptation planning and policy interventions.

While extensive research has explored the individual health impacts of extreme heat on older adults, less attention has been paid to population-level heat exposure. Giacomo Falchetta led a team of international researchers, including experts from the Euro-Mediterranean Center on Climate Change, Boston University, and the Ca’ Foscari University of Venice, who quantified chronic and acute heat exposures across different age groups globally.

“By 2050, over 23% of the global population aged over 69 could be living in climates where acute heat exposure exceeds the critical threshold of 37.5°C, compared to 14% in 2020,” commented Giacomo Falchetta, a researcher at CMCC and Ca’ Foscari University of Venice. The study also predicts an additional 177 to 246 million older adults may face dangerous acute heat exposure by mid-century. “Asia and Africa are expected to bear the brunt of these effects, with potentially the least capacity to adapt,” added Deborah Carr, Professor of Sociology at Boston University and co-author of the study.

The researchers underscored that regions experiencing an ageing population and increasing heat exposure will likely experience heightened demands for social and healthcare services. The projected increase in heat-related risks could potentially strain healthcare services, necessitating innovative policy interventions and a proactive approach to climate adaptation planning. These findings are critical for informing health assessments and climate adaptation planning in vulnerable regions across the globe.

More information: Giacomo Falchetta et al, Global projections of heat exposure of older adults, Nature Communications. DOI: 10.1038/s41467-024-47197-5

Journal information: Nature Communications Provided by CMCC Foundation

Essential Nutrients Linked to Slower Brain Aging: A Study

Scientists have long focused on understanding the brain to promote healthier ageing, yet preventing cognitive decline remains a challenging frontier. While risk factors for accelerated brain ageing are well-documented, strategies to mitigate cognitive decline through nutrition have been less explored until recent advancements. A pioneering study published in Nature Publishing Group Aging by researchers from the University of Nebraska–Lincoln’s Center for Brain, Biology and Behavior and the University of Illinois at Urbana-Champaign has illuminated how specific nutrients may profoundly influence brain health as individuals age.

Under the leadership of Aron Barbey, this study took a novel approach, fusing cutting-edge techniques from neuroscience and nutritional science. The team’s focus was on identifying a unique nutrient profile that could enhance cognitive performance. The study involved 100 cognitively healthy adults aged 65-75, who underwent a comprehensive range of assessments, including demographic data collection, physical measurements, and activity evaluations. Blood plasma, cognitive tests, and MRI scans were then analysed for nutrient biomarkers following a fasting period.

The findings revealed two distinct patterns of brain ageing: accelerated and slower-than-expected. Participants exhibiting slower brain ageing displayed a specific nutrient profile characterised by beneficial fatty acids (such as vaccenic and gondoic acids), antioxidants (like cis-lutein and zeaxanthin), vitamin E variants, and choline. These nutrients are notably prominent in the Mediterranean diet, which has previously shown associations with improved brain health.

Aron Barbey, the Mildred Francis Thompson Professor of Psychology, underscored the study’s significance in advancing nutritional research on brain ageing: “We investigated specific nutrient biomarkers known for their potential health benefits, aligning with extensive research on the Mediterranean Diet’s positive impacts. Our findings identify promising nutrient biomarker patterns linked to cognitive performance and brain health.”

Unlike previous studies reliant on food frequency questionnaires, susceptible to recall biases, this study stands out for its integration of brain imaging, blood biomarkers, and validated cognitive assessments. Barbey emphasised the study’s holistic approach, which moves beyond traditional cognitive tests to explore brain structure, function, and metabolism through diet and nutrition.

Looking ahead, the researchers are eager to delve deeper into the role of the identified nutrient profile in supporting healthy brain ageing. Barbey outlined plans for randomised controlled trials to isolate specific nutrients associated with cognitive function and brain health. These trials could potentially pave the way for targeted nutraceutical interventions, offering a hopeful future for brain health research.

Moreover, Barbey is co-editing a forthcoming unique collection for the Journal of Nutrition titled “Nutrition and the Brain — Exploring Pathways to Optimal Brain Health Through Nutrition,” inviting contributions that will further illuminate the nexus between nutrition and cognitive function.

This study represents a significant leap forward in our understanding of how nutrition influences cognitive performance and brain health as individuals age. By integrating sophisticated methodologies from neuroscience and nutritional science, the research identifies promising nutrient biomarker patterns and underscores the potential for targeted nutritional strategies to support healthy brain ageing. As research progresses, these insights hold promise for informing future interventions aimed at enhancing brain health and cognitive function through dietary approaches, highlighting the importance of our work in this field.

More information: Christopher E. Zwilling et al, Investigating nutrient biomarkers of healthy brain aging: a multimodal brain imaging study, European Journal of Nutrition. DOI: 10.1038/s41514-024-00150-8

Journal information: Nature Aging Provided by University of Nebraska–Lincoln